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JWH-018 also known as(1-pentyl-3-(1-naphthoyl)indole), is a synthetic cannabinoid research chemical, and EZRC are the first to stock.
It is an carbazole based cannabinoid that is the carbazole analogue of JWH-018and so is perfect for researchers in countries where other cannabinoids are controlled. Like chemicals such as THJ-018 and AB-PINACA, it has relatively low in-vitro CB1/CB2 activity but is still interesting for researchers who like to study that type of synthetic cannabinoid. Buy JWH-250 Online.
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Scientists can conduct experiments to determine the basic data on the material, such as melting points, and solublities etc. and see how it compares and contrasts with the data from similar chemicals.
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JWH-018 is a full agonist of both the CB1 and CB2 cannabinoid receptors. With a reported binding affinity of 9.00 ± 5.00 nM at CB and 2.94 ± 2.65 nM at CB . JWH-018 has an EC50 of 102 nM for human CB receptors, and 133 nM for human CB receptors. JWH-018 produces bradycardia and hypothermia in rats at doses of 0.3–3 mg/kg, suggesting potent cannabinoid-like activity
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